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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RB1 All Species: 34.24
Human Site: T373 Identified Species: 62.78
UniProt: P06400 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06400 NP_000312.2 928 106159 T373 V N V I P P H T P V R T V M N
Chimpanzee Pan troglodytes XP_509777 1075 122190 T520 V N V I P P H T P V R T V M N
Rhesus Macaque Macaca mulatta XP_001100383 928 106126 T373 V N V I P P H T P V R T V M N
Dog Lupus familis XP_534118 897 103170 T342 V N V I L P Q T P V R T V M N
Cat Felis silvestris
Mouse Mus musculus P13405 921 105320 T367 A N V V T P H T P V R T V M N
Rat Rattus norvegicus P33568 920 105007 T366 A N M V T P H T P V R T V M N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514098 917 104520 T364 V Q L I P P Q T P V R A V M N
Chicken Gallus gallus Q90600 921 104417 T363 V N H V L P Q T P V R A A M N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001071248 903 102339 T359 I A I P V P Q T P I R A A M T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395096 1006 113492 V380 R Q K D I T N V T P V S T A T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790323 774 86478 V230 T N E R V L R V V C E E G G V
Poplar Tree Populus trichocarpa B9GLX8 1035 114624 T431 A N S K M A A T P V S T A M T
Maize Zea mays Q3LXA7 1010 111475 T416 N S K M A P S T P V S T A M T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.2 99.3 90 N.A. 90.4 89.7 N.A. 81.3 73 N.A. 53.9 N.A. N.A. 23 N.A. 26.4
Protein Similarity: 100 86.3 99.5 93 N.A. 94.9 95.1 N.A. 88.2 84.1 N.A. 70.9 N.A. N.A. 42.9 N.A. 42.6
P-Site Identity: 100 100 100 86.6 N.A. 80 73.3 N.A. 73.3 60 N.A. 33.3 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 80 66.6 N.A. 53.3 N.A. N.A. 13.3 N.A. 6.6
Percent
Protein Identity: 22.1 23.2 N.A. N.A. N.A. N.A.
Protein Similarity: 40.4 42.1 N.A. N.A. N.A. N.A.
P-Site Identity: 40 40 N.A. N.A. N.A. N.A.
P-Site Similarity: 40 53.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 8 0 0 8 8 8 0 0 0 0 24 31 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 8 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % G
% His: 0 0 8 0 0 0 39 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 8 39 8 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 16 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 0 16 8 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 8 8 8 0 0 0 0 0 0 0 0 85 0 % M
% Asn: 8 70 0 0 0 0 8 0 0 0 0 0 0 0 62 % N
% Pro: 0 0 0 8 31 77 0 0 85 8 0 0 0 0 0 % P
% Gln: 0 16 0 0 0 0 31 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 8 0 0 8 0 0 0 70 0 0 0 0 % R
% Ser: 0 8 8 0 0 0 8 0 0 0 16 8 0 0 0 % S
% Thr: 8 0 0 0 16 8 0 85 8 0 0 62 8 0 31 % T
% Val: 47 0 39 24 16 0 0 16 8 77 8 0 54 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _